Dopamine supplements reddit. Personally, I can vouch for higher DHA supps .

Dopamine supplements reddit The brand I take, brain feed, base their products on scientific data and their tyrosine is the world's 1st natural 800mg capsule from fermented corn. I have experimented with both tyrosine and 5-htp and have a good idea of what serotonin and dopamine make me feel like and my preferences. Adderall both releases dopamine from your brain, and stops its reuptake, so more dopamine gets held between your neurons. 5-4h. In fact, the dopamine loaded crash following extreme sports has been theorized to be more addictive and rewarding than the actual rush that adrenaline junkies seem to be pursuing. Members Online A dopamine releasing agent (DRA) is a type of drug which induces the release of dopamine in the body and/or brain. Here is a quick list to give you some ideas: L-tyrosine: A precursor for dopamine synthesis L-phenylalanine: Similar to L-tyrosine, also a precursor for dopamine synthesis Polygala tenuifolia: Acts as a dopamine reuptake inhibitor DLPA, or DL-phenylalanine, is likewise a well-absorbed precursor to dopamine. My memory, sadly, is far from perfect. Like, something like Life Extension's "Dopamine Advantage" which contains some flower that increases dopamine, can that harm things? Are those neurotransmitter tests accurate? Ashwandganda may help with cortisol levels. conformational change). You could have a billion dopamine receptors and soo much dopamine but you need to train your brain to release it at whatever time you may feel it is the most important. Natural dopamine although bacopa is much stronger and similar I think to levodopa used for Parkinson’s. The supplements in *asterisks* make the biggest difference in my experience. Take the NAC in the morning which helps raise glutamate levels. 23 votes, 20 comments. So I was looking for substances that increase dopamine and energy without exacerbating anxiety. I take basic fish oil and a supplement which has Maca root, Ashwagandha & L-Theanine. Monks use blue lotus as one of the herbs in a mixture they use for detoxing people from withdrawals. One of the richest, cheapest sources of tyrosine & tryptophan, precursors to dopamine & serotonin? If you can, get as much as you feel comfortable with and consume ad libitum. Adrenal hormones. With supplements such as DLPA, 5-HTP, and SAM-E the studies and individual testimonials I've seen all revolve around having the patience to wait and experience the benefits, but if it doesn't work within 3 or 4 weeks move onto a new supplement or get prescribed a different antidepressant. Glutamate is like the regulator of dopamine. It does not only upregulate receptors, but the whole dopamine system. Pavlovian A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. Summary, key points, and the best clips from today's episode with Kyle Gillett: Tools for Hormone Optimization in Males (lots of talk about increasing testosterone, porn's affect on dopamine, & supplements) Mucuna Pruriens, also known as the dopamine bean or the velvet bean, is a tropical legume located in Africa and tropical Asia. Read on multiple sites they help produce and raise healthy dopamine levels This is responsible for synthesising neurotransmitters. It isn't strong enough but i dont want to go any higher. 7 dietary supplements have clinical evidence of upregulating dopamine receptors, and several supplements and activities can boost circulating dopamine levels. MDMA to an extent but there are plenty of supplement choices that are better. There are supplements that 'boost' and support dopamine production, but these are not what I'm looking for. If you want to increase natural dopamine production then you should take something that affects hormones or the dopamine production process. Comes to proof that reddit is not as smart as it thinks. I actually just posted two articles on this, the important thing to remember is there are different types of dopamine receptors, I don't have time to write up a big post here but the D2 receptor is one of the things Adderall works through, but long term or high usage can lead to death of the D2 receptors. As a regular MDMA user I can assure you that the serotonin boosting effects of C are definitely not placebo. Maybe it was actually not a study, but a post on Reddit. I miss myself, I miss feeling things, I miss feeling present in my own body, etc. The "dopaminergic system" is responsible for motivation and reward, and I think NAC has been shown to subtly improve this by increasing dopamine function. The change for me has been night and day. Members Online When I look online for help with this the only recommendations I get are Dopamine boosting supplements but my understanding is that doing that would make my problem much worse. These things may not expedite the healing process as a whole, but should at least I am trying to understand what is really happening. Im also interested in the correlation between low dopamine and the development of lower T. L-Dopa is the precursor to dopamine, and so it elevates dopamine, but this is linked to tremendous side effects and downregulation. Lithium orotate from botany. Could also be a mixup with L-Dopa, which is after all a metabolite of L-Tyrosine. Literally all the supplements I’ve ever found helpful are dopamine boosters in some way. (serotonin syndrome). Not yet on ADHD meds, and obviously hoping those will help. Yes and no. Along with it take Curcumin C3 Complex (I take Sports Research brand) because it does increase dopamine, but you better take this every other day, and ditch it for couple of days sometimes. Upregulates the D2 receptors. A great natural supplement that boosts Dopamine is L tyrosine, the recommended dosage is one 800mg capsule a day. So I’m more susceptible to phenylalanine toxicity. (I have slow COMT, so this helps). Look into Wellbutrin (bupropion). Ask your doc about a NSSRI such as wellbutrin. There are supplements that do cross it that either are converted to neurotransmitters on the other side or stimulate production, and they do work to increase levels of that transmitter. Griffonia if you want a plant: precursor of Serotonin. I took a 23 and Me test and found out that I have a gene that stops my body from breaking down phenylalanine at a normal rate. But I was wondering if anyone had any other ideas. You could try taking EGCg supplement, or quercetin - both slow COMT down. Masturbation in moderation is generally healthy, but excessive porn use can have serious adverse effects. g. Melatonin inhibits dopamine. News, articles, discussion, studies about dopamine and other neurotransmitters. Looking for a natural boost. Obviously they're nothing like the real thing, but you will notice a difference Methylation in a nutshell is what the body does to speed up enzymes and make chemical reactions happen and it is absolutely CRITICAL to neurotransmitters being created and being utilised properly, dopamine is not immune to this and there’s plenty of evidence of how the supplements provided above have dramatically boosted people’s energy and Norepinephrine–dopamine reuptake inhibitor (NDRI) , major depressive disorder, atypical antidepressant , Epileptic seizures , ADHD, alleviate sexual dysfunction, weight loss, releasing agent of dopamine and norepinephrine (NDRA), similarly to other cathinones , Wellbutrin SR and XL A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. It's the is the more direct precursor to dopamine than tyrosine is (the pathway is typically phenylalanine -> tyrosine -> L-DOPA -> dopamine -> norepinephrine etc). ) To increase levels of both dopamine and serotonin, one possible efficient approach would be: Supplement helps with anxiety and mood (backed by 3 comments) Product provides energy and appetite suppression (backed by 2 comments) Supplement provides noticeable difference in mood and well-being (backed by 3 comments) Users disliked: Product may cause insomnia and sleep disturbances (backed by 2 comments) Honestly, I think this is more of a discipline thing rather than a supplement thing. For supplements, it depends on the sourcing, manufacturing and storage processes. It's protective against damage and modulates dopamine circuits. 2. L-tyrosine to have a positive affect on both? IT is a rate iimited dopamine precursor. It’s kind of the “5-htp equivalent” for dopamine. (Some MAOI raise both, though) But let's see what works: For Serotonin: -5-HTP or Tryptophan (its precursor). Dopamine is released when you have something pleasant and unexpected happening to you. The self-improvement will benefit you so much more than having a magic supplement fix your dopamine addiction Dopamine based stimulants will deplete your Sodium levels so make sure you're getting enough of your electrolytes; Sodium, Potassium etc. Yes sleep, exercise and diet is good but what worked for me was supplements that help me naturally raise dopamine and also lower my cortisol levels. Desire (dopamine) is the root of all suffering. Vitex Agnus Castus, also known as Chaste berry, has long been used as a treatment for sexual disorders and insufficiency. On a personal psychological note you should get into eastern philosophy particularly Buddhism. Feb 13, 2025 · Low dopamine levels. Improves sleep latency, sleep quality & sense of being rested after a night’s sleep, relaxation, daytime psychomotor vigilance, cognitive ability, neuroplasticity. This means protecting and supporting the dopaminergic neurons (SN and VTA), improving and maintaining dopamine receptor sensitivity, and increasing dopamine production. Might make you fall right asleep afterwards, but imo it’s much more comprehensive in resolving brain issues than individual amino acid supplementation. I recommend trying bulk supplements l tyrosine as I have found all of their products high quality and when I first took l tyrosine I bought from my local kings it made me irritated and tired so I gave up on it, then I decided to try a different brands version and when I tried l tyrosine I got all the positive effects the internet had to claim. Any input on the supplements is greatly appreciated. Furthermore, some supplements which boost Serotonin tend to decrease Dopamine. hydrophobic), whereas for dopamine re-uptake inhibitors it is enthalpy-driven (i. L-tyrosine or N-acetyl-l-tyrosine are better options that will effectively raise dopamine levels and are safe to supplement long-term, although work even better when cycled. Work on improving your mindfulness and self-control first, then start considering supplements. . The herbs are: Salvia Miltiorrhiza, and Thunbergia A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. L-Dopa freely converts to dopamine but L-Tyrosine I think you have to understand what you want to do first. r/AboutDopamine: Subreddit - Dopamine. Anybody ever try any supplements to boost dopamine levels? I just picked up some L-Tyrosine, L-Theanine, Phosphatidylserine, fish oil and multi vitamin hoping to help. Some common symptoms of low dopamine levels can include low energy or sex drive, weight changes, tremors, constipation, mood swings, muscle cramps, hallucinations, loss of balance, and difficulty sleeping. C & E Should strictly avoid supplements containing copper, methionine, SAMe or SSRI’s Lab Tests: Whole Blood Histamine CPT #83088, Homocysteine CPT #83090 (Overrmethylation Lab Panel) Test Indicators: High SAM/SAH ratio, Specifically, the enzymes responsible for synthesizing retinoic acid are highly expressed in dopamine-rich areas of the brain, such as the mesolimbic system. D3 only makes me feel better in very large single doses if 50K IU, so I only do that once or maybe twice a week. Or there is the "maybe" before the goal. Good ones can be fine, and likely even better than eating fish itself. I'm fairly certain I am dopamine deficient so I did a bit of research on the best supplements that increase dopamine. There are vitamin D receptors in areas of the brain where dopamine is produced. Not a place for discussion of illicit and illegal compounds. (Tyrosine, or D- / L-tyrosine, is also a dopamine precursor, but phenylalanine tends to convert more efficiently. 5mg is almost too much inhibition. The receptor 5-HT2c is one that mediates the release of dopamine and adrenaline, generally as it becomes more active dopamine is lowered and adrenaline is released in higher amounts. My concern would be if SAM-e only increases dopamine or is weighted to heavily on one side of the equation But more, this article talks about what vitamins your body needs to make dopamine - the thing we are really after! (The amino acid tyrosine is first turned into L-dopa, which is then made into dopamine. As far as supplements, in all my years of research and supplementation I haven't found anything that's worth the money/effort/effect or doesn't have a very short lived boost that will just rebalance itself shortly making In this post I'll mainly focus on NDRI's or Norepinephrine and dopamine reuptake releasers and/or inhibitors. EDIT2: Hey, front page folks, ELI5 is explicitly not for actual 5-year-olds. But studies show increases in dopamine release as well as production from the “fight or flight” adrenal response. "If you do this, maybe I will get something. This is NOT related to natural DRI's (Fructus Akebiae, Chaenomeles Speciosa). (To be confirmed) Fasting is good but you have actually made that up about precursors, precursors occur before the rate-limit of the actual neurotransmitters usually, it's different from having an exogenous source or an agonist that disrupts the natural production/uptake of neurotransmitters or their receptors. I would recommend Ginkgo Biloba, Mucuna, CoQ10, Vitamin D, Rhodiola Rosea, Choline, Rosemary, Nefiracetam, Omega 3, B complex Supplement, L-theanine, and ionic magnesium. com Feb 12, 2025 · I believe I am dopamine deficient. I have my specific reasons for wanting to lower my dopamine. Go get a third or even fourth opinion if you have to! Supplements can really help without access to medication. And I have tried “dopamine fasting” but I always seem to fail anything long term. In a nutshell, I think these are the most important supplements to aid in neurotransmitter support, especially given that alcohol, drugs, medications and other supplements listed in this thread, utilize these vitamins and minerals to have their beneficial effects in the first place, causing a potential lack of these vitamins and minerals overtime. So any dopamine produced In the body is stuck there - having no effect on your mood but increasing blood pressure. I have heard of L tyrosine but I’m confused on which brand and if I should get Oct 23, 2024 · I do long fast and it gets real boring without eating carbs to stimulate those neurotransmitters. However, dysregulation of dopamine can lead to mania and psychosis. Practice mindful deep breathing also gut micro biome is important where dopamine and serotonin is manufactured, I don’t recommend supplementing dopamine/serotonin without solving the root issue first Blue lotus has two strong alkaloids that regulate dopamine pathways and are said to be incredibly helpful for fixing damage from past drug abuse. Some natural methods & supplements which can help to boost dopamine include: sunlight exposure (full body) nutrient rich diet based on animal foods (red meat, shellfish, wild caught seafood, eggs, raw dairy, fruits) Choline, DMAE, manganese (reduces dopamine synaptic activity), zinc, P5P(B6) which increase GABA, Vit. In it she explains why and how to fix it through amino acid supplements, food and excercise. So many people saying placebo here. This supplement has become more popular after Andrew Huberman’s podcast on dopamine. Is this a side affect of meds? (I take methylphenidate for ADHD). I'm looking for any supplements that can lower dopamine or process it quickly like magnesium glycinate. Mucuna will acutely increase dopamine because it enters the dopamine synthesis cycle after the rate-limiting step unlike L-tyrosine. A porn addiction and compulsive sexual behavior recovery peer support forum. Has anyone found that the two conditions are linked? And as such found certain supplements e. I know, for example, you can buy L-Dopa over the counter. The goal is to raise the tonic rate of dopamine release - raise your baseline. It helped me 1-2 years ago with the sa They simply provide supplements that in some way or the other would boost the effectiveness of various facets associated with the dopamine network. Yes, lots of different supplements can raise dopamine levels. It can be bought as a supplement. Dopamine precursors: L-Tyrosine and L-Phenylalanine are used as supplements, and L-Dopa is found in both supplements and prescription medicine. There aren't many dopamine sensitizing agents in existence with scientific backing, but through my research I've concluded Bromantane and ALCAR fit that description. Look into dopamine detox regime if you want to solve the pattern of dopamine deprivation. Members Online On a supplemental level take l-tyrosine for dopamine and 5-htp for serotonin. L-Tyrosine, DHEA, Testosterone, Estrogen, Dihydrotestosterone, GABA, Bromocriptine, Cabergoline, Oxytocin and L-Phenyalanine will all increase dopamine production and because they only enhance the natural production of dopamine, rather than just forcing You could look into mucuna and bacopa. Take 1g a day. true. It's a NDRI, a noreponephrine-dopamine-reuptske-inhibitor. A DRI the mechanism of action at the dopamine transporter (DAT) for dopamine releasers/substrates is entropy-driven (i. Fix your sleep and treat the depression first. Your second doc is a joke. Works, but can be quite dangerous if abused. May lower dopamine. In mice, lack of developmental vitamin D in mum-mouse led to dopaminergic abnormalities in the offspring. Best supplements for dopamine production/lack of motivation aka severe adhd? I currently only take Magnesium supplements but 100mg Elvanse. We would like to show you a description here but the site won’t allow us. Alternative suggestions aside from supplements Edit: Motivation = dopamine= B6 (p5p) converting tyrosine to dopamine. There are several different mechanisms to boost dopamine. Watch his video on dopamine and the analogy of the tidal wave pool. Probably better off with some supplement, like Mucuna, known also as broad beans, which can be eaten raw but only young and small, cause cooking destroys L-Dopa which is the immediate precursor of dopamine. If you get a good effect from them, it lends credence to the idea. Some people produce less dopamine. That's when you get a high dopamine release. this is a hypothesis (i wouldn't be able to cite this), but it would probably wouldn't be a great idea to have medicine that does directly increases the level of dopamine in the body. If it runs too fast, you get low dopamine levels. When you take l phenylalanine or l tyrosine you provide building blocks for the body to create dopamine If you take l dopa the body will think there is already enough dopamine in the body, or even too much dopamine depending on the dose, and this will create a negative feedback loop which can/ will create issues in the long run. For months I’ve thought phenylalanine was the best way to go ‘for me’ because it’s at the top of the chain for dopamine and norepinephrine. A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. COMT is an enzyme responsible for breaking down dopamine. [2] Dopamine is a neurotransmitter linked to feelings of reward, excitement, and pleasure. Morning: In addition to that you need the dopamine push when you wake up, for that take DL-Phenylalanine from Life Extention on empty stomach. Are there any supplements, natural or otherwise, or dietary suggestions, that can boost my presumably low serotonin/dopamine? Essentially, a replacement for my alcoholic coping mechanism? Alterations of dopamine receptor expressions by supplements, herbs or nootropics are not necessarily anything significant enough to produce neuronal changes to effect mental health, in fact, this rarely is of any significance in the real world. Creatine's Effects on Serotonin and Dopamine Vit D3, however, does increase dopamine receptors. Most of them you should be keeping in the fridge after opening. I actually think they have low dopamine, the need to raise that dopamine is what makes them look more active than the others or to simply put it they are extroverts, they strive for the stimulation that will raise their dopamine levels to optimal level, you can see this in women vs men, women have a base line dopamine level higher than men by A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. When you quit one drug you substitute it for another. However, it wasn't until recently that scientists examined the compounds in the plant and discovered that many of them can reduce prolactin as much as dopamine itself (7). Members Online Although this study was performed on two monkeys only, there was thus no support for the view that chronic intermittent hyperactivity of the dopamine system may be related to an upregulation of striatal D2‐dopamine receptors. I came across l-tyrosine, n-acetyl l-tyrosine, phenylalanine, and mucuna pruriens, but I cannot figure out which one works best. Any dopamine produced by tyrosine in the body, as a result of taking B6 with tyrosine, cannot make it into the brain. Go to Supplements r/Supplements • by [deleted] View community ranking In the Top 1% of largest communities on Reddit. After experiencing some magnesium deficiency (occasional eye twitching, nightly calf cramps when short on sleep) I decided to supplement it with ZMA - magnesium citrate, zinc and B6. It is known for its high content of L-Dopa, the precursor to Dopamine. Tyrosine hydroxylase, dopamin receptors, dopamine expression, striatal and hippocampus dopamin levels and provides protection to dopamin neurons as well. Dopamine and other neurotransmitters cannot cross the blood-brain barrier. These supplements can benefit serotonergic drugs i. Both L-Tyrosine and L-Phenylalanine can be found in diet, and endogenously they experience a rate-limited conversion to L-Dopa by tyrosine hydroxylase. (that inhibits dopamine reuptake) - but I'd rather stick to my supplements. Energy = b vitamins especially NAD+ boosters like NR, niacine, NMN etc. e. But adequate magnesium supports healthy brain function in general through other neurological systems, and rectifying a deficiency could reasonably be expected to result in improved mood, motivation and concentration - things typically associated with "improving dopamine function". Long-term L-Dopa supplementation has potential to downregulate Dopamine synthesis. 2 herbs have been shown to enhance or augment the release of dopamine in various regions of the brain. It is thought to be majorly responsible for anxious and depressive symptoms. ————————————————— Your body also needs several vitamins and minerals to create dopamine, including iron I am mostly concerned with how Dopamine-improving supplements might interfere with official medications. Lions mane, L tyrosine, L theanine, Caffeine, ALCAR, and if you can get your hands on it: Modafinil are all very good options to boost dopamine and serve as a decent replacement to meds. Ive tried the below: Lithium Magnolia Bark Bacopa Theanine 5HTP All of these cause anxiety/adrenaline issues. It's used to help quit smoking, against narcolepsy, around seventh in line for what doctors prescribe against depression, and may be used as an "if all else fails" ADHD medication, but it targets the dopamine reuptake which we all know is a great part of what messes us up. L-tryptophan is also a precursor melatonin. Great post. I think my dopamine binge was probably video games and other things. 15 votes, 26 comments. Not recommended. TL;DR: Addictive behaviors like porn, gambling, drug use, etc. People buy lottery tickets when they think that "maybe" they will win. So basically if you remove the need to make creatine, the methionine cycle can turn faster, which in turn turns the folate cycle faster, which in turn turns the BH4 cycle faster - ergo, more neurotransmitters. " Think of the lottery at the casino. Many cases of curing anhedonia or fully reversing years of stimulant abuse in 14-20 days. Ergo; if you slow it down (like with caffeine), levels go up for a while. The goal isn't to simply increase dopamine. To answer your question in one sentence, magnesium has no effect on dopamine. " Uridine, along with CDP Choline, promotes the growth of new dopamine receptors in the brain by activating D1 and D2 receptor signaling, helping to prevent dopaminereceptor burn out, especially in brains with fewer dopamine receptors. Vitamin C is a cofactor to the Enzyme Dopa Decarbocylase (DDC) wich is responsible for converting 5htp to serotonin, and L-Dopa to dopamine. That specifically targets the dopamine receptors to help boost dopamine. Personally, I can vouch for higher DHA supps Dopamine upregulation is hardly relevant if your brain is only going to release it in response to chemical stimuli. downregulate dopamine receptors over time. See full list on healthline. However, unlike parkinsons, drug induced Parkinsonism is usually due to prolonged blockage or damage to dopamine cells or receptors so increasing dopamine may or may not work in all cases. I can relate to you minus the alcohol binge. In terms of Omega 3 Fish Oil, it may be better for you to have a Fish Oil supplement higher in DHA rather than EPA; especially if you're taking Adderall for ADHD. Risperidone is an awful drug, but necessary to lower dopamine, which is its main function. By letting go of attachments you are exiting the hamster wheel of dopamine. bio Reishi ultra concentrated from ND Sabroxy from ND Tigers milk/lions mane mushroom (maybe both) Boron is good but ND is a better deal Thorne's SnyaQuell (I don't like it because I think it's unbalanced and not all the stuff in it are in the optimal forms) alternatively OmegaTau-v from ND although the other one could be a good preworkout Agmatine sulfate- lots of FLOWERING QUINCE EXTRACT & CATUABA EXTRACT have shown to inhibit DAT (dopamine transporter) = more dopamine. This mechanism helps optimize mental function and improve both mood and cognition. A beneficial tool is the book The Mood Cure by Julia Ross. Personally I have had immediate results with the supplements l-tyrosine and dlpa Is there a supplement known to inhibit the reuptake of dopamine? By reuptake inhibitor, I refer to a supplement that can prevent dopamine from rapidly dissipating and ensure it's readily available in the brain. A dopamine deficiency may not cause physical or mental health conditions on its own. Less vitamin d = less dopamine. 0mg was leaving me manic, but 2. I also have impaired Serotonin synthesis, so reuptake inhibition there is actually a good thing (noting that most drugs affect a couple of transmitters usually). But, as an overview: dopamine regulates motivation, attention, emotional regulation, and executive functions (which allow you to do things that are mundane or tedious). Whether it's supplying the necessary vitamins (b6) to up the conversion of the protein building blocks (l-tyrosine) in the sequence to dopamine, reducing oxidative stress thereby increasing dopamine (ginkgo, etc), increasing cAMP and thereby increasing dopamine (forskolin) etc I see probiotic supplements is linked to the same thing, and considered researching that. semi-hydrophilic. You can see them below - serotonin, dopamine, and norepinephrine. Glycine: empty stomach, 2h before sleep, (Amino-acid, neurotransmitter) HL 0. However, it may indicate a problem. Fwiw, if you want to see what he effect of boosting dopamine levels is, you could try any L-DOPA supplement. I take 1 capsule before work and it has helped me with feeling motivated and alert. Normal, healthy dopamine production depends on a wide variety of factors, but many medical professionals believe that your brain's dopamine production will return to pre-substance misuse levels over a period of 90 days A subreddit designed for discussion of supplements and nutraceuticals; for health, performance, or any intended (or not intended) purpose. I now also remember reading, that long term use of Dopamine-precursor can disrupt the balance of Dopamine and Serotonin, which in itself would warrant caution. Wish I would have found this 3 weeks ago as I spent probably 20 hours since then reading every study on all supplements that might help with the lack of energy, motivation and moderate Generalized Anxiety Disorder I experience sometimes. Take it with your adderall for a better peak and easier comedown, or take it as the last adderall is wearing off in order to mitigate the comedown almost entirely. 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